艾滋病合并隐球菌脑膜炎患者实验室相关指标分析

探讨艾滋病及其合并隐球菌脑膜炎患者实验室相关指标的变化及其临床意义。方法将我院收治的58例艾滋病患者，分为26例艾滋病患者(单纯感染组)、32例艾滋病合并隐球菌脑膜炎患者(合并感染组)，分别对脑脊液和外周血常规及生化指标、T细胞亚群进行检测，分析两组间实验室检测指标的差异。结果合并感染组的脑脊液蛋白质为(601.28±...

Experimental analysis of acquired immunodeficiency syndrome patients with cryptococcus neoformans meningitis

Objective To study the clinic laboratory characters of AIDS with cryptococcus neoformans meningitis coinfection patients. Methods 58 cases of AIDS patients in our hospital were selected. All the cases were divided into two groups, 26 AIDS patients were infection group, while those with meningitis were coinfection group. T lymphncytes,liver function, blood routine test were detected by the immunological, biochemical methods. Results Compared with the infection group, cerebral protein in coinfection group was high(601.28±545.24) mmol/L, t =0.494, P＞ 0.05], CL and GLU in coinfection group were low( 121.571 ± 5.255) mmol/L and ( 1.944 ± 0.678) mg/L, t = 0.129, 1.984,P＞0.05]. In coinfection group, the counts of lymphocyte, CD3, CD4, and CD8 were (495.0± 141.1), (479.9±137.4), (35.1 ± 32.2), (413.9 ± 104.8) colls/μL separately. They were all lower than those in control group ( t=2.236, 2.007,2.767,1.997, P ＜ 0.05 ). Conclusiions The counts of CD4 in AID Spatients with cryptococcus neoformans meningitis is significantly decreased, so in the clinical, pathogen detection should be consided to the patients with CD4 ＜ 100/μL, and the CD3 or CD8 decreased obviously.