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职业性接触性荨麻疹的研究进展
引用本文:邹颖,王学民. 职业性接触性荨麻疹的研究进展[J]. 国际皮肤性病学杂志, 2011, 37(5). DOI: 10.3760/cma.j.issn.1673-4173.2011.05.011
作者姓名:邹颖  王学民
作者单位:上海市皮肤病医院皮肤与化妆品研究室,200443
摘    要:职业性接触性荨麻疹是一种常见的职业性皮肤病,表现为接触职业中特定致病原后出现的局部或系统性过敏症状。根据发病机制可分为免疫性及非免疫性接触性荨麻疹,后者更为常见。职业中所接触的动植物蛋白、化学物、药物等均为该病的危险因素,并可导致较为严重的不良后果。因此,皮肤科医师在该病的诊断中,应注意掌握详细的病史资料,并进行可疑致病物的皮肤试验。针对致病原采取必要的预防措施是该病治疗的关键,若疾病已经发生,有效的三线治疗方案则成为必须。

关 键 词:荨麻疹  超敏反应  职业  免疫

Advances in occupational contact urticaria
ZOU Ying,WANG Xue-min. Advances in occupational contact urticaria[J]. International Journal of Dermatology and Venereology, 2011, 37(5). DOI: 10.3760/cma.j.issn.1673-4173.2011.05.011
Authors:ZOU Ying  WANG Xue-min
Abstract:Occupational contact urticaria (OCU) is a common occupalional dermatosis characterized by local or systemic anaphylaxis after contact with occupational antigens. It is divided into two subtypes according to physiopathology: immunological CU and nonimmunological CU, and the latter occurs more frequently. Many substances in workplaces can cause allergic reactions and even serious consequences, such as plant or animal proteins, chemicals, drugs, etc. Physicians should perform careful interrogation, clinical examination and appropriate skin tests to identify causative allergens. The treatment of OCU should be emphasized on preventive measures targeting allergens. Once the contact with an eliciting substance occurs, effective three-line therapy is warranted.
Keywords:Urticaria  Hypersensitivity  Occupations  Immunity
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