18F-FDG PET-CT双时相显像结合高分辨率CT诊断孤立性肺结节的价值

目的 探讨18F-FDG PET-CT双时相显像结合高分辨率CT (HRCT)对孤立性肺结节(SPN)的鉴别诊断价值。方法 经CT证实符合SPN的病例173例，应用PET-CT技术对SPN病例进行双时相显像及同机HRCT，早期显像于注射18F-FDG后50 ～60min，并行HRCT，延迟显像于注射后2～2.5 h进行...

Dual phase time scan combine high resolution CT to diagnose solitary pulmonary nodule by 18F-FDG PET-CT

Objective To evaluate the role of dual phase scan combine high resolution computerized tomography (HRCT) by 18F-FDG PET-CT imaging in the diagnosis of solitary pulmonary nodule(SPN).Methods 173 patients with SPN demonstrated by CT, All these patients underwent dual time point combine HRCT 18F-FDG PET/CT imaging.The imaging protocol included the early imaging combine HRCT of PET-CT at 50-60 min and delayed imaging of PET at 2-2.5 h post injection 18F-FDG.The standardized uptake value (SUV) was calculated for both time points.All results were expressed as the percentage change in SUV.According to characteristic in focal morphology by HRCT found, general inspection and diagnosis were benign or malignant,It was compared the result and following up result.Results Histopathology demonstrated or following up result 41 patients with malignant lesions and 132 patients with benign lesions.The SUV of malignant lesions was SUV 6.26±0.72 in early imaging,, and 6.88±0.74 in delayed imaging.The retention index of malignant lesions was(42.50±3.87)％.The SUV of benign lesions was 2.84±0.41 in early imaging,and 2.73±0.36 in delayed imaging.The retention index of benign lesions was (26.90±7.23)％.Conslusions 18F-FDG PET-CT dual time point imaging combine HRCT is a simple practical method and accurate ratio high for the diagnosis of SPN.The method will be widely clinically practised.