| 流感病毒感染与急性心肌梗死关系的研究 |
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| 引用本文： | 关秀茹,马学华,蒋丽鑫,林春艳,韩丽,杜柏岩.流感病毒感染与急性心肌梗死关系的研究[J].国际检验医学杂志,2011,32(16):1800-1801,1804. |
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| 作者姓名： | 关秀茹 马学华 蒋丽鑫 林春艳 韩丽 杜柏岩 |
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| 作者单位： | 哈尔滨医科大学附属第一医院检验科,150001 |
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| 基金项目： | 黑龙江省自然科学基金资助项目 |
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| 摘 要： | 目的探讨流感病毒(IV)感染与急性心肌梗死(AMI)的关系。方法采用ELISA法检测74例AMI患者和77例对照组IV-A、IV-B抗体及白细胞介素-18(IL-18)、超敏C反应蛋白(hsCRP)的水平,并对冠心病危险因素进行调查。结果 AMI组IV-AIgG、IV-BIgG阳性率及IL-18、hsCRP水平均显著高于对照组,差异有统计学意义(P<0.01),且IgG水平与IL-18、hsCRP呈正相关。校正冠心病危险因素前后,IV-A和IV-BIgG阳性均与AMI有相关性。结论 IV感染可能激发或加重冠状动脉内炎性反应,IL-18和hsCRP参与AMI的病理过程。
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| 关 键 词： | 正黏病毒科 动脉粥样硬化 心肌梗死 白细胞介素18 |
Research on relationship between influenza virus infection and acute myocardial infarction |
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| Guan Xiuru,Ma Xuehua,Jiang Lixin,Lin Chunyan,Han Li,Du Baiyan.Research on relationship between influenza virus infection and acute myocardial infarction[J].International Journal of Laboratory Medicine,2011,32(16):1800-1801,1804. |
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| Authors: | Guan Xiuru Ma Xuehua Jiang Lixin Lin Chunyan Han Li Du Baiyan |
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| Institution: | Guan Xiuru,Ma Xuehua,Jiang Lixin,Lin Chunyan,Han Li,Du Baiyan (Department of Laboratory Diagnostics,the First Clinical College of Harbin Medical University,150001,China) |
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| Abstract: | Objective To study the association between influenza virus infection and acute myocardial infarction (AMI).Methods 74 patients with AMI(AMI group),77 healthy controls were enrolled(control group). For all subjects,antibodies specific for IV-A and IV-B,levels of interleukin-18 (IL-18) and hypersensitive C-reactive protein (hsCRP) were measured by ELISA. Meanwhile,the risk factors of coronary heart disease were investigated.Results The positive rates of antibodies specific for IV-A and IV-B IgG,and levels of ... |
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| Keywords: | orchomyxoriridae atherosclerosis myocardial infarction interleukin-18 |
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