| 脐血CIK细胞的研究进展 |
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| 引用本文： | 肖琼. 脐血CIK细胞的研究进展[J]. 国际儿科学杂志, 2011, 38(5): 500-502. DOI: 10.3760/cma.j.issn.1673-4408.2011.05.024 |
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| 作者姓名： | 肖琼 |
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| 作者单位： | 山东省脐带血造血干细胞库研发中心,济南,250102 |
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| 摘 要： | 细胞因子诱导的杀伤(CIK)细胞是在多种细胞因子共同作用下诱导而来的一种免疫效应细胞，具有增殖速度快、杀瘤活性高、杀瘤谱广及主要组织相溶性复合体非限制性杀瘤的优点。脐血CIK细胞的增殖速度、杀瘤活性优于成年人CIK细胞，移植后移植物抗宿主病发生率低，因而受到广泛的关注。
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| 关 键 词： | 脐血 细胞因子诱导杀伤细胞 免疫治疗 |
Research advances in cord blood cytokine induced killer cells |
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| XIAO Qiong. Research advances in cord blood cytokine induced killer cells[J]. International Journal of Pediatrics, 2011, 38(5): 500-502. DOI: 10.3760/cma.j.issn.1673-4408.2011.05.024 |
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| Authors: | XIAO Qiong |
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| Abstract: | Cytokine induced killer (CIK) cells are immune effector cells generated from mononuclear cells induced by many cytokines. CIK cells have several advantages, such as rapid proliferation, broad spectrum killing activity, high tumoricidal activity and non-major histocompatibility complex restriction. Recently, cord blood derived CIK cells have attracted extensive concerns because of its faster proliferation, higher tumoricidal activity and lower incidence of GVHD compared with adult peripheral blood derived CIK cells. This paper will review the biological characteristics, clinical application and research advances of cord blood derived CIK cells. |
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| Keywords: | Cord blood Cytokine induced killer cells Immunotherapy |
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