冠心病患者血脂尿酸血浆纤维蛋白原测定及临床意义

目的：探讨冠心病患者血脂、尿酸、血浆纤维蛋白原的变化及相互关系。方法：对106例冠心病患者和50例对照者采血测定血脂、尿酸、血浆纤维蛋白原，并分析三者的相关性。结果：冠心病组TC、TG、LDL—C、Lp（a）、uA、Fib均高于对照组（P＜0．05）；冠心病组组间TC、LDL—C、Lp（a）、Fib有差异（P＜0．05），且稳定型心绞痛组的TC、LDL—C、Lp（a）显著低于不稳定型心绞痛组和急性心肌梗死组，而急性心肌梗死组的Lp（a）、Fib显著高于心绞痛组。血脂、尿酸、血浆纤维蛋白原三者间均无相关性。结论：血脂、尿酸、血浆纤维蛋白原作为冠心病的危险因素。

Clinical Significance of Serum Lipids Blood Uric Acid and Fibrinogen in Coronary Heart Disease Patients

Objective： To explore the levels of serum lipids, uric acid, fibrinogen and their association of coronary heart disease. Method： Serum lipids,uric acid and fibrinogen in 106 patients with various CHD were measured and compared with those in 50 healthy controls. Result： The levels of TC,TG, LDL - C, UA, Lp（a） ,Fib were significant higher in CHD group than those in healthy group （P 〈0.05）,moreover,the levels of TC,LDL- C, Lp（ a） were greatly decreased in SAP group compared in other CHD cases,the level of Fib was greatly increased in AMI group compared in the other two groups. There was no correlation among the three. Conclusion： Serum lipids, uric acid, fibrinogen may be the independent risk factors of CHD.