| ezrin在乳腺癌中的表达及其临床意义 |
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| 引用本文： | 李文广,张燕妮,颜海,凌黎,李京微,姜海英,李艳芳.ezrin在乳腺癌中的表达及其临床意义[J].中国综合临床,2007,25(1):699-701. |
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| 作者姓名： | 李文广 张燕妮 颜海 凌黎 李京微 姜海英 李艳芳 |
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| 作者单位： | 江苏省徐州市肿瘤医院肿瘤内科,221005;江苏省徐州市肿瘤医院普外科,221005;江苏省徐州市肿瘤医院病理科,221005; |
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| 基金项目： | 徐州市卫生局科技计划项目 |
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| 摘 要： | Objective To study the expression and clinical significance of ezrin in breast carcinoma. Methods Immunohistuchemieal staining(S-P) was used to detect the expression of ezrin in 63 cases of breast car-cinoma samples. Results Among these 63 samples,the total expression rates of ezrin were 55.56% (35/63). With the increasing of axillary lymph nodes metastasis and clinical staging,the rates of expressing of ezrin elevated (P<0.05),which was remarkably lower in patients whose disease-free survival(DFS) was > 5 years,or those whose DFS≤5 years or died within five years(P<0.05) ,but the expression of ezrin was not correlated with tumor size,age and menopausal status (P>0.05). Conclusion The expression of ezrin may contribute to prognostic e-valuation for breast carcinoma.
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| 关 键 词： | 乳腺癌 免疫组化 预后 |
Expression and clinical significance of ezrin in breast carcinomas |
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| Abstract: | |
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| Keywords: | ezrinEzrinBreast carcinomaImmunohistochemistryPrognosis |
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