老年口腔鳞癌前哨淋巴结活检的临床病理研究

目的:探讨前哨淋巴结活检(sentinel lymph node biopsy,SLNB)预测老年口腔鳞癌患者颈部淋巴结转移的价值及提高病理准确性的方法。方法:对18例临床及影像学检查阴性的老年口腔鳞癌患者,采用1%美兰示踪定位识别前哨淋巴结,随后行全颈淋巴结清扫,将SLN做连续病理切片检查。结果:18例患者中检出SLN14例,其中13例的SLN能准确预测颈部淋巴结的转移状况。结论:应用美兰能准确定位SLN,前哨淋巴结连续病理切片活检结果,能准确预测颈部淋巴结的转移状况,具有潜在的临床应用价值。

Clinical pathological evaluation of sentinel lymph node biopsy of oral squamous cell carcinoma in elderly patients

Objective:To evaluate the clinical value of sentinel lymph node biopsy (SLNB) on the prediction of the neck lymph node metastasis of oral squamous cell carcinoma (OSCC) in the elderly patients and to study the methods to rise its accurate rate by using the successive pathological section of SLN. Methods:18 cases of primary OSCC patients with clinical negative were injected 1% methylene blue and taken SLNB, then SLN was dissected. The successive pathological sections of SLN were detected after operation. Results:14 of 18 cases were detected with SLN, among which 13 cases SLN had predicted neck metastasis. Conclusion:The method to predict the status of metastasis of neck in OSCC by SLNB with methylene blue and successive pathological section of SLN is simple and exact and has a potential clinical value.