Cytostatic activity of Achillea ageratum L. |
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| Authors: | M A Gómez M D García M T Sáenz |
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| Affiliation: | Laboratory of Pharmacology, Faculty of Pharmacy, University of Sevilla, 41012 Sevilla, Spain. |
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| Abstract: | The cytostatic activity of a chloroform extract and two isolated compounds from Achillea ageratum L. (Asteraceae) was determined in vitro against Hep-2 and McCoy cells. The chloroform extract exhibited a high degree of growth inhibition compared with the values obtained with the 6-mercaptopurine (positive control) against both cultures. Stigmasterol and beta-sitosterol, isolated from the chloroform extract, showed a high degree of growth inhibition. |
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| Keywords: | Achillea ageratum Hep‐2 cells McCoy cells antimitotic activity cytostatic activity stigmasterol β‐sitosterol |
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