银屑病的瘙痒特征及相关因素分析

目的调查银屑病患者中瘙痒发生率、瘙痒程度等临床特征及其影响瘙痒的相关因素。方法采用问卷调查的形式调查了112例银屑病患者,评价其瘙痒特征及影响瘙痒的相关因素。结果 112例银屑病患者中83%存在不同程度瘙痒,相关分析显示:患者瘙痒与否与年龄、疾病活动度呈显著相关(P0.05),而与患者性别、病程、家族史、吸烟、饮酒及身体质量指数(BMI)无相关性,瘙痒程度与银屑病皮损面积及严重程度指数(PASI)评分、浸润程度呈显著相关(P0.05),而与红斑、鳞屑无相关性。结论大多数银屑病患者存在不同程度的瘙痒症状,年纪越大、皮损越广泛、浸润程度越高以及处在进展期的银屑病患者瘙痒越剧烈。

Prevalence and Clinical Characteristics of Pruritus in Patients with Psoriasis

Objective In order to study the prevalence and clinical characteristics of pruritus in patients with psoriasis.Methods A questionnaire was sent out to 112 patients with a diagnosis of psoriasis,to assess clinical characteristics of pruritus in patients with psoriasis.Results Out of 112 patients,83％ patients suffered from different degrees of itching.The presence of pruritus depend on age,as well as it was observed during the extension of psoriatic lesions and independent of sex,duration of disease,family history of psoriasis,alcohol,smoking habits or body mass index (BMI).Correlation analysis showed that there was positive correlation between the intensity of pruritus and the mean psoriasis area,the psoriasis area and severity index (PASI) score and the infiltration of the lesions.Conclusion Pruritus is a common feature in psoriasis.Patients which are older,in progressive stage,more psoriasis area,higher PASI score and more infiltration of the lesions may suffered from more intensity of pruritus.