慢性肝炎肝硬化患者中医证型与血清肝纤维化指标的关系

测定１６０例慢性肝炎肝硬化患者的血清肝纤维化樗物透明质酸（ＨＡ）、Ⅲ型前胶原（ｈＰＣⅢ）和Ⅳ型胶原（Ⅳ－Ｃ）３项，以探讨中医证型与上述指标的关系。结果显示，各中医证型组的肝纤３项指标均较对照组升高，但发迹有各自的特点，其中肝郁脾虚组的平均升高幅度最小。同时发现，湿热中阻组肝纤３元月 显著性升高，肝肾阴和瘀血阳络级以ＨＡ、ｈＰＣⅢ升高为主，脾肾阳虚组以ＨＡ、Ⅳ－Ｃ升高为主。提示测定上述指标对慢性肝病

Relationship Between the Serum Indices of Liver Fibrosis and TCM Syndromes Types in Liver Cirrhosis due to Chronic Hepatitis

In order to probe into the relationship between the TCM syndrome types and the five indices of fibrotic markers of liver in serum, the HA, hPC I , IV - C in 160 of liver cirrhosis patients induced by chronic hepatitis were examined. Results showed that the 5 indices in all TCM syndrome types were all higher than the control group, each with its specificity. The increased amplitude in the group of liver - stagnant, spleen - deficiency was the least one. It was also found that the 3 indices of liver fibrosis in the group of internal blockade of damp - heat were markedly increased; it was mainly the increase of HA, hPC I in the group of yin-deficiency of both liver - kidney and obstruction of collaterals by static blood; but it was mainly the increase of HA, W - C in the group of Yang - deficiency of spleen and kidney. This demonstrated that the above indices were of significance in TCM syndrome typing for chronic hepatic victims. Lingering of damp -heat may be the trigger factor for liver fibrosis in which blood stasis was present during the whole course of liver fibrosis.