老年慢性心力衰竭患者甲状腺功能异常的变化规律

目的探讨老年慢性心力衰竭(CHF)患者甲状腺功能异常的变化规律。方法对100例CHF患者抽取晨间肘静脉血,用放射免疫法测定FT3、FT4及TSH。结果老年人CHF甲状腺功能异常患病率39.56%(36/91),甲状腺功能减退(下文中简称:甲减)15.38%(14/91),亚临床甲减24.18%(22/91);且甲状腺功能异常患病率与心衰病程呈正相关(P<0.001),与心功能程度呈负相关。结论对CHF患者常规进行甲状腺功能检测很有必要,可提高甲减性心脏病及CHF合并甲状腺功能异常的正确诊断。CHF合并甲减患者在常规抗心衰治疗基础上补充甲状腺素治疗可以改善心功能。

The variation of abnormal thyroid function in elderly patients with chronic heart failure

Objective To investigate the variation of abnormal thyroid function in elderly patients with chronic heart failure （CHF）. Methods YT3 ,FT4 and TSH were detected by radioimmunoassay from 100 patients with CHF in the morning. Results The prevalence of abnormal thyroid function in elderly patients with chronic heart failure（CHF）was 39.56% （36/91）, the prevalence of hypothyroidism in that patients was 15.38%（ 14/91 ）and the prevalence of subclinical hypothyroidism in that patients was 24.18%（22/91 ）. Furthermore, the correlation between the prevalence of abnormal thyroid function and the duration of heart failure was positive （P 〈 0.001 ）, while the correlation between the prevalence of abnormal thyroid function and degree of cardiac function was negative. Conclusion It is necessary to do thyroid function examination in pa- tients with chronic heart failure （CHF）. It could improve the correct diagnosis of hypothyroidism heart disease and the chronic heart failure combined with abnormal thyroid function. Thyroxine in addition to the conventional treatments may improve the heart function in the patients with chronic heart failure（CHF） and hypothyroidism.