不同体质量指数2型糖尿病患者代谢状况分析

目的 探讨不同体质量指数（BMI）2型糖尿病患者胰岛功能、脂代谢、血尿酸等代谢状况.方法 按BMI将233例2型糖尿病患者分为超重组与正常组,同时测定血糖、C肽、血脂、血尿酸等指标,用彩色多普勒超声进行肝胆B超的测定,分析超重组与正常组上述指标有无差异.结果 超重组的腰围、臀围、空腹C肽水平及脂肪肝、高血压患病率均显著高于正常体质量组（P＜0.01）,超重组总胆固醇、甘油三酯显著高于正常组（P＜0.05）.结论 2型糖尿病超重患者存在胰岛素抵抗、脂代谢异常、血压升高、脂肪肝等代谢紊乱,而上述因素加重大血管并发症的发生,因此减轻体质量,有利于对各种代谢紊乱的控制,减少大血管并发症的发生与发展.

The study of metabolic characteristics in Type 2 Diabetes Mellitus with Different BMI

Objective To study the metabolic characteristics in type 2 diabetes mellitus with different BMI.Methods 233 patients with type 2 diabetes mellitus were divided into 2 groups. The first group was the BMI ＜25kg/m2 ,the second group with BMI ≥25kg/m2. The blood sugar、 blood-fat 、blood uric acid、type-B ultrasonic of liver were analyzed. Results The waistline、hip circumference、limosis c-peptide 、total cholesterol 、triglyceride and morbidity of fatty liver and hypertension of the second group were higher than the first group. Conclusion Over weigh patients of type 2 diabetes had IR、hyperlipemia、hypertension 、fatty liver. The rate and the severity of the artery diseases in type 2 diabetes mellitus increased wit the increase of the BMI. So weigh reduction could decrease the development of the artery diseases in type 2 diabetes.