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Persistent intestinal bleeding due to severe CMV-related thrombocytopenia in a preterm newborn |
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| Authors: | Alberto Berardi Eugenio Spaggiari Chiara Cattelani Maria Federica Roversi Monica Pecorari Tiziana Lazzarotto |
| Affiliation: | 1. Dipartimento Integrato Materno-Infantile, Terapia Intensiva Neonatale, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy;2. Struttura Complessa di Microbiologia e Virologia, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy;3. Unità Operativa di Microbiologia, Azienda Ospedaliero-Universitaria Policlinico S. Orsola Malpighi, Bologna, Italy |
| Abstract: | The optimal threshold for neonatal platelet transfusions in sick newborns is still uncertain. We report a congenital cytomegalovirus (CMV) infection in a premature neonate with severe thrombocytopenia who subsequently presented with necrotizing enterocolitis and intestinal bleeding. The baby recovered after platelet transfusions were discontinued and the therapy was switched from intravenous ganciclovir to oral valganciclovir. We discuss both measures, speculating on the key role of platelet transfusions. |
| Keywords: | Cytomegalovirus intestinal bleeding thrombocytopenia congenital infection newborn |