清开灵治疗小儿病毒性咽炎82例疗效观察

目的 探讨清开灵对病毒性咽炎的治疗作用。方法 将临床确诊为病毒性咽炎的82例患儿，随机分为清开灵治疗组和利巴韦林治疗组。清开灵组：清开灵冲剂0．5g／次，3～4次／d口服，连崩4—5d；利巴韦林组：口服利巴韦林颗粒（新博林，Ribavirin Granules）10mg／（kg·d），3次／d，疗程4～5d。观察两组疗效。结果清开灵组在退热、咳嗽、咽痛、咽充血消失时间均较利巴韦林组显著缩短（P〈0．01）；治疗总有效率也明显提高（P〈0．01）。结论清开灵治疗小儿急性病毒性咽炎疗效明显优于利巴韦林，应作为治疗小儿病毒性咽炎的推荐首选药物。

The clinical analysis of the 82 children's Treatment of viral Pharyngitis with QingKaiNing.

Objective To outline therapeutic results of QingKaiNing in treatment viral Pharyngitis. Methods 82 patients were randomly divided into QingKaiNing treatment group and ribavirin treatment group. The dose of QingKaiNing 0. 5 g/Each, 3 -4 each daily, Continued 4 -5 d, and Ribavirin Granules 10 mg/（ kg · d） ,3 each daily, for 4 -5 days. Results In comparison to ribavirin treatment group, patients in QingKaiNing treatment group needed shorter time for symptom free, extinction of cough, Pharyngodynia and nasal obstruction, there were statistically significant differences（ P 〈 0.01 ） ;and had higher effective rate, there was statistical significant difference （P 〈 0. 01 ）. Conclusion The therapeutic effects of QingKaiNing on viral Pharyngitis was better than ribavirin, which suggested that QingKaiNing would be the chief medicine treatment for viral larygitis in children.