公安民警代谢综合征影响因素的配对病例对照研究

目的 探讨公安民警代谢综合征(MS)发病的遗传、生活行为和职业影响因素.方法 采用1∶4配比病例对照研究方法,以天津市公安民警2010年体检资料为基础,根据2004年中华医学会糖尿病分会制定的MS工作定义(CDS标准),随机抽取新确诊的708名MS患者为病例组;按性别、年龄(±1岁)随机选取2007至2010年体检均正常的2832名健康公安民警作为对照组.对既往各种可能的危险因素暴露史进行流行病学调查,相关资料应用条件logistic回归模型分析.结果 单因素条件logistic回归分析发现15个因素与MS发病有关.多因素条件logistic回归结果,高血压家族史(OR=2.406,95%CI∶1.946～2.975)、糖尿病家族史(OR=1.301,95%CI∶1.043～1.623)、吸烟(OR=1.357,95%CI:1.010～1.823)、打鼾(OR=1.268,95%CI∶1.043～1.543)、高工作强度(OR=4.603,95%CI∶3.767～5.623)、职业应激事件(OR=1.524,95%CI∶1.209～1.922)、警种为治安警(OR=1.453,95%CI∶1.127～1.872)和警种为刑侦警(OR=2.792,95%CI∶2.168～3.596)是MS独立的危险因素,而奶制品(OR=0.782,95%CI∶0.619～0.989)是MS的保护因素.人群归因分值结果,若依次控制MS的危险因素吸烟、打鼾、高工作强度和职业应激事件,MS发病可分别减少16.26%、11.71%、56.87%和8.97%.结论 MS已成为影响公安民警健康的重要的公共卫生问题,应尽早针对相关的行为和生活方式、职业因素采取预防控制措施,减少MS的发病,提高公安民警的健康水平.

A matched case-control study on the risk factors of metabolic syndrome among policemen

Objective To investigate the life style, genetic and occupational risk factors of metabolic amination data of Tianjin Policemen in 2010, 708 patients with MS were randomly selected as cases, which were matched with 2832 healthy controls on the basis of sex and age (± 1 year ).An epidemiological investigations on the past exposure status of several possible risk factors was conducted, and the data were analyzed with conditional logistic regression.Results Fifteen factors related to exposure were identified for MS through univariate conditional logistic regression analysis.Multivariate conditional logistic regression analysis suggested that, sevrisk factors analysis showed that the control of smoking, snoring, work intensity, occupational stressful events can decreased the risk of MS to 16.26%, 11.71%, 56.87% and 8.97%, respectively.Conclusion Metabolic syndrome has became a significant public health problem among policemen, it's necessary to take measures on life style, occupational risk factors for reducing the incidence of MS, and improving the health level among policemen.