Familial clustering of intracerebral hemorrhage: a prospective study in North Carolina. |
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| Authors: | M J Alberts M O McCarron K L Hoffmann C Graffagnino |
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| Affiliation: | Department of Medicine, Division of Neurology, Duke University Medical Center, Durham, NC, USA. |
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| Abstract: | Few studies have assessed the frequency of familial clustering in intracerebral hemorrhage (ICH). Of 144 patients with ICH prospectively assessed, 14 (9.8%) had a positive family history of ICH (FH+). Four pedigrees had more than two affected family members. Comparisons between FH+ and FH- probands demonstrated no significant differences in race, age, sex, ICH type or location. An underlying genetic etiology may account for familial clustering in some ICH patients. |
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