Partial seizure-like symptoms in borderline personality disorder

The clinical presentation of borderline personality disorder (BPD) bears a striking resemblance to the behavioral alterations associated with temporal lobe epilepsy. Using the Limbic System Checklist-33, we found that BPD subjects reported more symptoms associated with partial seizures than did control subjects. BPD patients also exhibited deficits on immediate and delayed recall of the Rey-Osterrieth Complex Figure and produced distorted drawings of the Rey Figure. Their degree of impairment correlated with their report of temporolimbic symptoms. Results are consistent with the proposal that temporolimbic dysfunction underlies the behavioral dyscontrol and affective dysregulation present in BPD.