实时三维斑点追踪成像评价PCI术后左心室收缩功能的临床研究

［摘要］目的评价经皮冠状动脉介入治疗（percutaneous coronary intervention，PCI）术后左心室收缩功能改善情况。方法收集冠心病患者（冠心病组）69例和对照组38例。记录对照组和冠心病组PCI术前和术后1，3，6个月常规超声参数及左心室整体长轴应变、左心室整体轴向应变、左心室整体径向应变、左心室整体面积应变数据。 结果冠心病组体重指数、收缩压、吸烟比例、心率、空腹血糖高于对照组（P＜0.05）。冠心病组左心室舒张末内径、左心室舒张末容积、左心室收缩末容积、左心房前后径均大于对照组，左心室射血分数、左心室短轴缩短分数、长轴应变、圆周应变、面积应变、径向应变均低于对照组（P＜0.05）。冠心病组术后1个月、3个月、6个月面积应变、长轴应变、圆周应变、径向应变均高于术前，术后3个月、6个月面积应变、长轴应变、圆周应变、径向应变均高于术后1个月，术后6个月面积应变、长轴应变、圆周应变、径向应变均高于术后3个月（P＜0.05）。面积应变、长轴应变、径向应变、圆周应变检查者内的相关系数分别为0.856、0.949、0.824、0.913，4个应变测量的可重复性良好。结论实时三维斑点追踪成像技术可以定量评价PCI术后左心室收缩功能改善情况。

Evaluation of left ventricular global systolic function in coronary heart disease patients after PCI by real-time three-dimentional specke tracking imaging#br#

［Abstract］Objective〖HTSS〗To evaluate the improvement of left ventricular global systolic function in coronary artery diseasepatients after percutaneous coronary intervention（PCI）, and then investigate the value of PCI. 〖WTHZ〗Methods〖HTSS〗According to coronary angiography, 107 suspected coronary artery disease patients were divided into two groups：coronary stenosis group(n=69), control group(n=38). All the conventional images and the three-dimentional full volume dynamic images of left ventricular were collected before and after surgery of 1 month, 3 months, and 6 months. The changes of left ventricular global longitudinal strain（GLS）, global circumferential strain（GCS）, global radial strain（GRS）, global area strain（GAS）,left ventricular ejection fraction(LVEF)， left ventricular shortening fraction(LVFS), left ventricular end-diastolic volume(LVEDV) and left ventricular end-systolic volume(LVESV) between preoperative and postoperativewere analyzed. 〖WTHZ〗Results〖HTSS〗The body mass index, systolic blood pressure, smoking rate, heart rate and fasting blood-glucose of coronary heart disease group were higher than those in the control group(P＜0.05). Left ventricular end-diastolic diameter,left atrial diameter,LVEDV and LVESV were higher than those in the control group(P<0.05). LVEF,LVSF,GLS, GCS, GAS,GRS were lower than those in the control group(P＜0.05). GLS, GCS, GAS,GRSof 1 month, 3 months and 6 months postoperatively were higher than those before operation. GLS, GCS, GAS and GRS of 3 months and 6 months postoperatively were higher than those of 1 month postoperatively. GLS, GCS, GAS and GRS of 6 months postoperatively were higher than those of 3 months postoperatively(P＜0.05).The correlation coefficients of GAS, GLS, GRS and GCS were 0.856, 0.949, 0.824 and 0.913, respectively. The repeatability of four strain measurements were good. 〖WTHZ〗Conclusion〖HTSS〗Real-time three-dimentional specke tracking imaging can quantitatively assess the improvement of left ventricular global systolic function in coronary heart disease patients after PCI.