高血压患者踝臂指数与尿微量白蛋白的相关性 |
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引用本文: | 甘毅,刘建义,谢丽璋,李应钦,任正康,张吉红,卢柳荷. 高血压患者踝臂指数与尿微量白蛋白的相关性[J]. 中国心血管病研究杂志, 2011, 9(5): 348-350 |
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作者姓名: | 甘毅 刘建义 谢丽璋 李应钦 任正康 张吉红 卢柳荷 |
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作者单位: | 甘毅,刘建义,李应钦,任正康(东莞市东坑医院内科,广东省,523451);谢丽璋(东莞市东坑医院防保科,广东省,523451);张吉红,卢柳荷(东莞市东坑医院功能科,广东省,523451) |
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基金项目: | 东莞市科技计划医疗卫生类科研项目 |
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摘 要: | 目的 探讨高血压患者踝臂指数(ABI)与尿微量白蛋白(MAU)的关系.方法 80例原发高血压患者经连续2次检查晨尿排除显性蛋白尿,采用多普勒超声法检测四肢动脉血压,计算ABI,分为ABI正常组(38例)和ABI减低组(42例),连续2次检查晨尿常规及MAU.结果 两组MAU阳性率分别为28.9%(11/38)和54.8%(23/42),MAU分别为(21±11)mg/L和(38±24)mg/L,差异均有统计学意义(P<0.05).直线相关性分析显示,ABI正常组ABI与MAU无显著相关(r=0.18,P>0.05),而ABI减低组ABI与MAU呈显著负相关(r=-0.63,P<0.01).结论 ABI减低的高血压患者MAU增加,提示ABI减低对评估高血压患者早期肾功能损害有参考价值.
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关 键 词: | 高血压 动脉粥样硬化 踝臂指数 尿微量白蛋白 |
Relationship between ankle-brachial index and microalbuminuria in hypertensive patients |
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Affiliation: | GAN Yi, LIU Jian-yi, XIE Li-zhang, et al. Department of Internal Medicine, Dongkeng People's Hospital of Dongguan, Dongguan 523451, China |
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Abstract: | Objective To study the relationship between ankle-brachial index (ABI) and microalbuminuria (MAU) in patients with essential hypertension. Methods ABI and MAU were measured in a total 80 hypertensive patients without urineprotein, and were divided into the normal ABI group (ABI I〉0.9, n=38 )and the low ABI group (ABI〈0.9,n=42). Results The group with low ABI had higher presence of MAU than the group of normal ABI (54.8% vs 28.9%, P〈0.05 ). The level of MAU in the low ABI group were significantly higher than those of normal ABI group [(38±24)vs (21±11)mg/L, P〈0.05]. The linear correlation analysis showed that the ABI of low ABI group was negatively related to MAU (r=-0.63,P〈0.01). Conclusion The hypertensive patients with low ABI have high MAU, and low ABI may be used to predict early kidney damage in hypertensive patients. |
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Keywords: | Hypertension Atherosclerosis Ankle-brachial index Microalbuminuria |
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