| 双黄连注射液在生物体内抗细菌内毒素的实验研究 |
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| 引用本文： | 王彦美,姜庆城,杨振中,杜凤礼.双黄连注射液在生物体内抗细菌内毒素的实验研究[J].山东医学高等专科学校学报,2002,24(1):33-35. |
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| 作者姓名： | 王彦美 姜庆城 杨振中 杜凤礼 |
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| 作者单位： | 1. 郯城县第一人民医院,山东,郯城，276100
2. 郯城县药品检验所 |
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| 基金项目： | 郯城县科技发展计划项目 (郯科字 0 10 60 9) |
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| 摘 要： | 目的 探讨双黄连注射液在生物体内抗细菌内毒素的效果。方法 观察双黄连注射液对内毒素休克小鼠的生存时间及对内毒素所致大鼠肝，肺，肾等病理改变的影响。用鲎试剂法测定用药后大鼠和人体血浆内毒素的含量变化。结果 双黄连注射液可明显降低动物和人体血浆内毒素含量，延长内毒素休克小鼠的平均生存时间，对内毒素所致大鼠的肝、肺，肾等损害具有保护作用。结论 双黄连注射液在生物体内具有显著的抗内毒素作用。
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| 关 键 词： | 双黄连注射液 生物体内 细菌内毒素 |
| 文章编号： | 1001-5426(2002)01-0033-03 |
| 修稿时间： | 2002年1月6日 |
EXPERIMENTAL RESEARCH ON THE EFFECT OF SHUANGHUANGLIAN INJECTION ON ANTIBACTERIAL ENDOTOXIN |
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| WANG Yan mei,JIANG Qing cheng,YANG Zhen zhong.EXPERIMENTAL RESEARCH ON THE EFFECT OF SHUANGHUANGLIAN INJECTION ON ANTIBACTERIAL ENDOTOXIN[J].Journal of Shandong Medical College,2002,24(1):33-35. |
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| Authors: | WANG Yan mei JIANG Qing cheng YANG Zhen zhong |
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| Abstract: | Objective To explore the effect of Shuanghualian injection on antibacterial endotoxin.Methods The effect of shuanghuanglian on the survival time of mice in shock caused by endotoxin and the pathological changes of liver,lungs and kidney induced by endotoxin were observed.Endotoxin concentrations in the plasma of rats and human body were measured through limulus test.Results Shuanghualian injection could effectively reduce endotoxin concentrations in the plasma of rats and human body,prolong the survival time of rats in shock caused by endotoxin and protect the livers ,lungs and kidneys from being damaged by endotoxin.Conclusion Shuanghuanglian injection can be effectively used to treat endotoxin. |
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| Keywords: | Shuanghuanglian injection In living creature Bacterial endotoxin |
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