评估丹尼斯克乳双歧杆菌Bi07及嗜酸乳杆菌NCFM对人体肠道消化系统微生态环境改善功效的研究

目的评估丹尼斯克乳双歧杆菌Bi07及嗜酸乳杆菌NCFM对人体肠道消化系统微生态环境改善效果。方法将符合要求的400名25～45岁志愿者根据男：女=1：1的比例随机分为安慰剂组、益生菌产品组2个组。所有400名志愿者，分别在试验第一天至最后一天服用对应产品，每天2次，分别于上午10点和下午4点服用，每次100g，持续3周。结果可有效改善人体肠道消化系统微生态环境，志愿者体内双歧杆菌、乳杆菌活菌数显著增加（P〈0．01），产气荚膜杆菌活菌数显著减少（P〈0．01）。结论连续服用丹尼斯克益生菌产品21d，每天200g，对人体肠道消化系统微生态环境的改善具有显著效果。

Study on evaluating the promote effect of danisco products on bifidobacterium lactis Bi07 and lactobacillus acidophilus NCFM on physical intestinal canal microbial eco-system

Objective To evaluate the promote effect of Danisco products Bifidobacterium Lactis Bi07 ＆ Lactobacillus acidophilus NCFM on physical intestinal canal microbial eco-system. Methods A 3- week randomized trial was conducted in 400 healthy persons aged from 25 to 45 years, with a male to female ratio of 1 ： 1, they were randomly divided into 2 groups： placebo group and probiotics group. Each group takes the corresponding products 100 g twice everyday at 10 a.m. and 4 p. m respectively. Re- suits Digestive system on microbial eco-system was effectively improved. The viable count of Bifidobacteria and Lactobacillus was significantly increased. The viable count of Clostridiumperfringen was signifi- cantly decreased. Conclusions Significant effectiveness on physical intestinal canal microbial eco-system were proved by intake Danisco probiotics products＂ 200 g per day for 21 days.