阳山县消灭丝虫病防治策略和技术措施的研究

为了消灭阳山县丝虫病 ,从 1 959年起对该县进行丝虫病流行病学摸底调查 ,发现共有 1 9个乡镇的 2 1 7个管理区有班氏丝虫病流行 ,平均人群微丝蚴率为 4 3 5%。据此提出以防治病原为主导的策略 ,制订出三项防治技术措施 :①在一个中度流行镇以海群生间歇双疗程法进行连续四年反复查治 ,微丝蚴率从查治前的 1 5 0 8%降至 0 4 5% ;②对连成一片且有固定食盐供应渠道的三个中度流行镇采用全民服食海群生掺拌食盐 ( 3g/kg)防治 6个月 ,微丝蚴率从 5 0 7%降至 0 4 3 % ;③查治结合重点村全民服药 ( 7岁以上人群全民用海群生 3g ,5天分服 ) ,共血检 1 3 2 58人 ,查出并治疗微丝蚴血症 1 5例 ,全民服药 1 8757人 ,巩固丝虫病防治效果。 1 980年经卫生部考核 ,微丝蚴率降至 0 0 0 %～ 0 2 5% ,达到基本消灭丝虫病标准。 1 988～ 1 992年进行纵向监测和 1 9个乡镇横向监测分别血检 60 85、2 80 1 2人次 ,均未发现微丝蚴血症者 ;分别解剖致倦库蚊 1 0 545、4 61 6只 ,均未发现有丝虫感染。 1 996年经省及卫生部考核达到消灭丝虫病部颁标准

Control Strategy and Technical Measures of Elimination of Filariasis in Yangshan County

This paper reported the control strategy and technical measures of elimination of filariasis in Yangshan county.217 villages in 19 towns had bancroftian filariasis prevalence and the average population microfilarial rate was 4.35%.The control strategy was pathogen control and three kinds of measures were taken:(1)In a moderately endemic town,DEC,two courses intermittently was used to treat infected villagers for four years and the microfilarial rate was reduced from 15.08% to 0.45%.(2)In three moderately endemic towns,DEC salt was used to substitute the normal salt supply for 6 months and the microfilarial rate was reduced from 5.07% to 0.43%.(3)In heavenly endemic villages,one course 5 days,DEC was given to all villagers,>7 years old and 18 757 persons were treated all together.In 1980,the microfilarial rate reduced to less than 0.25%.From 1988 to 1994,through longitudinal and transversal surveillance,6 085 and 28 012 blood samples were tested respectively and 10 545 and 4 616 Culex quinquefasceatus were dissected respectively,and all of people and vectors were negative.In 1996,the county reached criterion of elimination of filariasis.