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Randomized controlled trial of internal and external targeted temperature management methods in post- cardiac arrest patients

Authors:	Xinqi Look Huihua Li Mingwei Ng Eric Tien Siang Lim Sohil Pothiawala Kenneth Boon Kiat Tan Duu Wen Sewa Nur Shahidah Pin Pin Pek Marcus Eng Hock Ong

Affiliation:	1. Ministry of Health Holdings, Singapore;2. Division of Research, Singapore General Hospital, Singapore;3. Emergency Medicine Residency, Singapore Health Services, Singapore;4. Department of Cardiology, National Heart Centre, Singapore;5. Department of Emergency Medicine, Singapore General Hospital, Singapore;6. Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore;g. Health Services and Systems Research, Duke-NUS Medical School, Singapore

Abstract:

Keywords:	TTM targeted temperature management OHCA out-of-hospital cardiac arrest ROSC return of spontaneous circulation ED emergency department MICU medical intensive care unit CCU coronary care unit R2TH ROSC to initiation of TTM R2TT ROSC to target temperature T2TT time from initiation of TTM to target temperature CPR cardiopulmonary resuscitation PEA pulseless electrical activity VF/VT ventricular fibrillation/ventricular tachycardia OR odds ratio CI confidence interval PCI percutaneous coronary intervention AICD automatic implantable cardioverter defibrillator CPC cerebral performance category OPC overall performance category IQR interquartile range Targeted temperature management Cardiac arrest Emergency department Neurological function Survival outcomes
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