PAG stimulation does not affect primary antibody responses in rats |
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| Authors: | R Noguchi C Hamada K Shimoji |
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| Affiliation: | 1. Department of Anesthesiology, Niigata University School of Medicine, Niigata 951 Japan;7. Department of Virology, Niigata University School of Medicine, Niigata 951 Japan;1. Fiddleheads Health & Nutrition, 25 Bruce Street, Kitchener, ON N2B 1Y4, Canada;2. CAMNR, 23679 Calabasas Road Suite 542, Calabasas, CA 91302, USA;1. Graduate Program in Neurobiology and Behavior, Columbia University Medical Center, New York, New York;2. Department of Psychiatry, Columbia University Medical Center, New York, New York;3. Department of Pharmacology, Columbia University Medical Center, New York, New York;4. Division of Developmental Neuroscience, New York State Psychiatric Institute, New York, New York;5. Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, New York |
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| Abstract: | Adult male rats, which had electrodes chronically implanted in the periaqueductal gray (PAG), were immunized with sheep red blood cells (SRBCs). The number of direct and indirect plaque-forming cells (PFCs) in the group receiving PAG stimulation after immunization did not differ significantly from that in the unstimulated group. Thus, the results indicate that short-term PAG stimulation does not suppress antibody-producing activity in the rat. |
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