雷尼替丁与奥美拉唑治疗消化性溃疡疗效分析

目的探讨雷尼替丁与奥美拉唑治疗消化性溃疡的临床疗效。方法将该院收治的消化性溃疡患者随机分为对照组和治疗组。其中对照组给予雷尼替丁口服,治疗组给予奥美拉唑口服,均治疗4周。1个疗程后观察两组患者的临床疗效及不良反应发生情况。结果治疗1个疗程后,对照组患者总有效率为76.19%,治疗组患者总有效率为93.02%,两者比较差异有统计学意义(P<0.05)。两组患者均有较轻微不良反应发生,停药后均自行消失。结论奥美拉唑治疗消化性溃疡的作用优于雷尼替丁,可显著提高临床总有效率,具有临床推广的意义。

The Comparison of the Efficacies Between Ranitidine and Omeprazole in the Treatment of Peptic Ulcer

Objective To compare the clinical efficacies between ranitidine and omeprazole in the treatment of peptic ulcer. Methods Patients with peptic ulcer admitted in our hospital were divided into control group and treatment group randomly. The control group was treated with ranitidine and the treatment group was treated with omeprazole. Both groups were treated for 4 weeks. The elinical efficacy and adverse reactions of the two groups were observed and compared after a course of treatment. Results After a course of treatment, the total effective rate of the control group was 76.19%, and that of the treatment group was 93.02%, the difference was statistically significant （P〈0.05）. All the patients of the two groups had mild adverse reactions, which disappeared after stopping drugs. Conclusion Omeprazole is superior to ranitidine in the treatment of peptic ulcer, which can increase the total effective rate obviously and is of significance in clinical promotion.