Identical twins with hypercalcaemia due to Lowe's syndrome

SIR, We describe the unusual diagnosis of Lowe's syndrome (oculocerebrorenalsyndrome) in identical twins at age 46 yr, who were referredto our institution for evaluation of hypercalcaemia and bonepain. Two 46-yr-old identical twin brothers presented with a 1-yrhistory of hypercalcaemia. Both had grown up in a foster carefamily and had required chronic haemodialysis for end-stage