超声支气管镜引导下经支气管针吸活检对纵隔恶性肿瘤的病理诊断

目的探讨超声支气管镜引导下的经支气管针吸活检（endobronchial ultrasound—guided transbronchial needle aspiration，EBUS—TBNA）在纵隔恶性肿瘤诊断中的价值。方法对2011年8月1日至2013年2月28日期间胸部cT诊断的148例纵隔肿瘤患者，病理诊断证实为恶性肿瘤的129例阳性患者的EBUS—TBNA检查资料总结，探讨其穿刺成功率及诊断敏感性。结果获得EBUS．TBNA阳性诊断的129例患者纵隔恶性肿瘤在扫查和活检中均能清晰显示，准确引导，118例取得阳性诊断，11例假阴性，穿刺成功率100％，诊断敏感性91．47％；无并发症发生。结论EBUS．TBNA是纵隔肿瘤确诊和新辅助化疗疗效评价的安全、实用性技术。

Pathologic diagnosis of mediastinal malignant mass by endobronchial ultrasound-guided transbronchialneedle aspiration

Objective To evaluate diagnostic value of endobronchial ultrasound-guided transbronchial nee- dle aspiration （EBUS-TBNA） in the pathologic diagnosis of mediastinal malignant mass. Methods Between August 2011 and February 2013, 129 patients of malignant mass corroborated by pathology among the cases with mediastinal malignant mass previously detected with CT scan（ 148 cases underwent EBUS-TBNA）. The techno- logical superiority of was evaluated. Results In 129 cases, mediastinal malignant masses were detected clearly and guided accurately by EBUS-TBNA. The positive results were obtained in 118 cases, the false negative re- sults were found in 11 cases. The success rate of biology and sensitivity of diagnosis by EBUS-TBNA in malig- nant tumor were 100% and 91.47% respectively. There was no complication in this group. Conclusions EBUS-TBNA seems a safe and useful technique in diagnosis of mediastinal malignant mass and can evaluate the response to neoadjuvant chemotherapy .