| 儿童急性杂合性白血病前期全血细胞减少1例报告并文献复习 |
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| 引用本文： | 秦兰,单丽娟,杜晓军,李巍. 儿童急性杂合性白血病前期全血细胞减少1例报告并文献复习[J]. 医学争鸣, 2009, 0(24) |
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| 作者姓名： | 秦兰 单丽娟 杜晓军 李巍 |
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| 作者单位： | 新疆医科大学附属中医院血液科;新疆医科大学中医学院;曲阜市中医院; |
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| 摘 要： | 目的:为了提高对儿童急性淋巴细胞白血病前期(Pre-ALL)全血细胞减少的认识,报告1例以全血细胞减少为前期表现的急性杂合性白血病(HAL)患儿临床资料并进行文献复习.方法:观察1例男性患儿,11岁,确诊HLA(T淋巴细胞和髓细胞杂合)8wk前发生过渡性、可恢复的全血细胞减少,且微小病毒B19抗体阳性.经正规化疗后可完全缓解.结果:经1疗程正规化疗完全缓解,但1mo后骨髓复发.结论:Pre-ALL的免疫表型可以为HAL(T淋巴细胞和髓系细胞杂合),提示预后不良.
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| 关 键 词： | 急性淋巴细胞白血病前期 全血细胞减少 急性杂合性白血病 微小病毒B19 |
Children transient pancytopenia preceding hybrid acute leukemia:One case report and review of literature |
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| QIN Lan,SHAN Li-Juan,DU Xiao-Jun,LI Wei. Children transient pancytopenia preceding hybrid acute leukemia:One case report and review of literature[J]. Negative, 2009, 0(24) |
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| Authors: | QIN Lan SHAN Li-Juan DU Xiao-Jun LI Wei |
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| Affiliation: | QIN Lan1,SHAN Li-Juan2,DU Xiao-Jun3,LI Wei1 1Department of Hematology,Affiliated Traditional Chinese Medicine Hospital,Xinjiang Medical University,Urumqi 830000,China,2Chinese Medicine University,3Traditional Chinese Medical Hospital of Qufu City,Qufu 273100 |
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| Abstract: | AIM:To report the development of children transient pancytopenia preceding acute lymphoblastic leukemia(Pre-ALL) in a case of Pre-ALL whose immunophenotype is coexpression of T lymphoid and myeloid markers.METHODS:A 11-year-old child suffered from transient pancytopenia,and developed hybrid acute leukemia(HAL).Whose diagnosis of HAL was preceded by a serologically confirmed Parvovirus B19(PB19) infection.RESULTS:After a transient complete remission to the initial therapy,the patient developed the overall re... |
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| Keywords: | preceding acute lymphoblastic leukemia pancytopenia hybrid acute leukemia parvovirus B19 |
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