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经纤维支气管镜肺灌洗治疗慢性阻塞性肺疾病急性加重期的临床疗效及对肺功能和血气的影响
引用本文:李奕,卓安山,冯琳,曾葭.经纤维支气管镜肺灌洗治疗慢性阻塞性肺疾病急性加重期的临床疗效及对肺功能和血气的影响[J].第四军医大学学报,2009(24).
作者姓名:李奕  卓安山  冯琳  曾葭
作者单位:解放军第411医院呼吸内科;上海市瑞金医院集团闵行医院老年科;
摘    要:目的:观察经纤维支气管镜肺灌洗治疗慢性阻塞性肺疾病(COPD)的临床疗效及对肺功能和血气的影响.方法:2007-06/2009-06,COPD急性加重期患者104例随机分为观察组和对照组,各52例.观察组在常规治疗的基础上采用经纤维支气管镜肺灌洗治疗;对照组仅采用常规治疗.观察两组的临床疗效及对肺功能和血气的影响.结果:观察组的显效率、总有效率明显高于对照组,两组比较差异有统计学意义(P<0.05).与治疗前比较,两组治疗后临床症状评分明显降低(P<0.05);FVC,PEFR和FEV1水平明显升高(P<0.05);PaO2和SpO2水平明显升高,PaCO2水平明显降低,差异有统计学意义(P<0.05).观察组的临床症状评分、肺功能指标(FVC,PEFR和FEV1)和血气指标(PaO2,PaCO2和SpO2)明显优于同期对照组,两组比较差异有统计学意义(P<0.05).结论:经纤维支气管镜肺灌洗治疗慢性阻塞性肺疾病的疗效显著,能够明显改善患者的临床症状、肺功能和血气状态.

关 键 词:经纤维支气管镜肺灌洗  慢性阻塞性肺疾病急性加重期  疗效  肺功能  血气  

Clinical curative effect of lung lavage by bronchoscopy in treatment with acute exacerbation of chronic obstructive pulmonary disease and its impact on pulmonary function and blood gas
LI Yi,ZHUO An-Shan,FENG Lin,ZENG Jia.Clinical curative effect of lung lavage by bronchoscopy in treatment with acute exacerbation of chronic obstructive pulmonary disease and its impact on pulmonary function and blood gas[J].Journal of the Fourth Military Medical University,2009(24).
Authors:LI Yi  ZHUO An-Shan  FENG Lin  ZENG Jia
Institution:LI Yi1,ZHUO An-Shan1,FENG Lin2,ZENG Jia1 1Department of Respiration,411th Hospital of PLA,Shanghai 200081,China,2Department of Geriatrics,Shanghai Minhang District Central Hospital,Shanghai 201100
Abstract:AIM:To observe the clinical curative effect of lung lavage by bronchoscopy in treatment with acute exacerbation of chronic obstructive pulmonary disease and its impaction on pulmonary function and blood gas.METHODS:From June 2007 to June 2009,104 cases of COPD at acute exacerbation phase patients were randomly divided into 2 groups,control group with 52 cases was treated with normal therapy and observation group with 52 cases was treated with lung lavage by bronchoscopy.The effective rate,clinical symptom s...
Keywords:lung lavage by bronchoscopy  acute exacerbation of chronic obstructive pulmonary disease  clinical curative effect  pulmonary function  blood gas  
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