| 腹部开放伤合并海水浸泡致犬急性心力衰竭临床特征 |
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| 引用本文： | 曹毅,高连如,陈宇,张宁坤,胡媛琴,费宇行,杨晔. 腹部开放伤合并海水浸泡致犬急性心力衰竭临床特征[J]. 医学争鸣, 2009, 0(21): 2296-2298 |
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| 作者姓名： | 曹毅 高连如 陈宇 张宁坤 胡媛琴 费宇行 杨晔 |
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| 作者单位： | 海军总医院心内科; |
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| 基金项目： | 海后司令部科研计划课题(04-3304) |
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| 摘 要： | 目的：观察犬腹部开放性损伤经海水浸泡后致急性心力衰竭的临床特征.方法：以成年杂种犬为实验动物犬随机分为腹部伤＋海水浸泡组（A组,n=8）和单纯腹部伤组（B组,n=8）.观察实验动物致腹部开放性损伤前、后及经海水浸泡2h后打捞出水不同时间点心律、心率（HR）、收缩压、舒张压、平均动脉压（MAP）、肺动脉嵌压（PAWP）、中心静脉压（CVP）、心输出量（CO）、心脏指数（CI）、B型脑利钠肽（BNP）、心肌酶谱、氧分压等相关指标.并于致伤前及致伤后4h行超声心图,测定LVEDV,LVESV,SV,LVEF.结果：A组在浸泡后HR、收缩压、舒张压、MAP,CVP均下降.至2h时,PAWP＆gt;18mmHg（1mmHg=0.133kPa）,CO减低伤前30%,CI,LVEDV,LVESV,SV,LVEF均较B组减低（P〈0.05）,肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）、BNP均较B组显著升高（P〈0.05）.结论：犬腹部开放伤合并海水浸泡后出现急性心力衰竭的特征.
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| 关 键 词： | 腹部开放伤 犬 海水 浸泡 急性心力衰竭 临床特征 |
Clinical characteristics of dogs after open abdominal injury and seawater immersion induced acute heart failure |
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| CAO Yi,GAO Lian-Ru,CHEN Yu,ZHANG Ning-Kun,HU Yuan-Qin,FEI Yu-Xing,YANG Ye. Clinical characteristics of dogs after open abdominal injury and seawater immersion induced acute heart failure[J]. Negative, 2009, 0(21): 2296-2298 |
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| Authors: | CAO Yi GAO Lian-Ru CHEN Yu ZHANG Ning-Kun HU Yuan-Qin FEI Yu-Xing YANG Ye |
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| Affiliation: | CAO Yi,GAO Lian-Ru,CHEN Yu,ZHANG Ning-Kun,HU Yuan-Qin,FEI Yu-Xing,YANG Ye Department of Cardiology,Navy General Hospital,Beijing 100037,China |
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| Abstract: | AIM:To observe the clinical characteristics of dogs after open abdominal injury and seawater immersion induced acute heart failure. METHODS:Adult mongrel dogs as experimental animals were randomly divided into open abdominal injury+seawater immersion group (A group n=8) and simple open abdominal injury group(B group n=8). To observe experimental animals caused by open abdominal injury before and after,and the seawater immersion after 2 h the water at different time points salvage cardiac rhythm,heart rate(H... |
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| Keywords: | open abdominal injury dog seawater immersion acute heart failure clinical characteristics |
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