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Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
Authors:Heather N. Grome  Michael Threlkeld  Steve Threlkeld  Charles Newman  Roosecelis Brasil Martines  Sarah Reagan-Steiner  Michael A. Whitt  Maria Gomes-Solecki  Nisha Nair  Mary-Margaret Fill  Timothy F. Jones  William Schaffner  John Dunn
Abstract:We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology of this syndrome, regardless of vaccination status, remains poorly understood.
Keywords:COVID-19   coronavirus disease   SARS-CoV-2   severe acute respiratory syndrome coronavirus 2   viruses   respiratory infections   multisystem inflammatory syndrome in adults   MIS-A   vaccines   vaccine-preventable diseases
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