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克拉玛依市特殊人群麻疹抗体水平及免疫效果研究
引用本文:石峰,黄玉莲,李君梅,许妮娜.克拉玛依市特殊人群麻疹抗体水平及免疫效果研究[J].中国预防医学杂志,2011(12):1021-1023.
作者姓名:石峰  黄玉莲  李君梅  许妮娜
作者单位:克拉玛依市疾病预防控制中心;克拉玛依市克拉玛依区疾病预防控制中心;
摘    要:目的了解育龄期女性、产妇及婴幼儿人群麻疹抗体水平分布,为制订预防策略提供依据。方法 2009年至2010年,选取育龄期妇女、产妇、新生儿及5~8月龄婴儿,采集血清用ELISA法进行麻疹抗体IgG水平检测,同时对5~8月龄婴儿进行麻疹疫苗免疫效果研究。结果育龄期妇女IgG抗体阳性率82.98%、保护率49.64%;产妇阳性率85.00%、保护率52.14%;新生儿阳性率79.17%、保护率47.50%,育龄期妇女与产妇间阳性率、保护率差异无统计学意义(χ2=0.27,P>0.05;χ2=0.23,P>0.05),GMT无明显变化。产妇与新生儿间阳性率、保护率差异无统计学意义(χ2=0.43,P>0.05;χ2=0.27,P>0.05),GMT无明显变化。5、6、7、8月龄婴儿免疫后抗体阳转率及抗体4倍增长率间差异无统计学意义(χ2=2.27,P>0.05;χ2=0.064,P>0.05);各组间GMT无明显趋势。结论建议在麻疹非流行期,为育龄期妇女接种麻疹疫苗。而在麻疹流行时,可将免疫初始月龄提前至6月龄。

关 键 词:麻疹  抗体阳性率  抗体阳转率  保护率  妇女  婴儿

Epidemiological study of measles antibody among women of childbearing age and infants in Kelamayi
SHI Feng,HUANG Yu-lian,LI Jun-mei,XU Ni-na.Kelamayi Municipal Center for Disease Prevention , Control,Kelamayi,Xinjiang ,China.Epidemiological study of measles antibody among women of childbearing age and infants in Kelamayi[J].China Preventive Medicine,2011(12):1021-1023.
Authors:SHI Feng  HUANG Yu-lian  LI Jun-mei  XU Ni-naKelamayi Municipal Center for Disease Prevention  Control  Kelamayi  Xinjiang  China
Institution:SHI Feng,HUANG Yu-lian,LI Jun-mei,XU Ni-na.Kelamayi Municipal Center for Disease Prevention and Control,Kelamayi,Xinjiang 834000,China
Abstract:Objective To investigate measles antibody levels among women of childbearing age and infants in Kelamayi.Methods Serum specimens were collected from 282 women of childbearing age(23-30 years),140 new mothers(25-34 years),120 newborns and 324 infants aged 5-8 months in 2009 and 2010.The levels of measles antibody were detected by ELISA.Results Measles antibody was detected in 82.98% of women of childbearing age,85.0% of new mothers and 79.17% of newborns,respectively.The protective levels of measles antibody...
Keywords:Meales  Positive rate  Seroconversion rate  Protection rate  Woman  Infant  
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