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Matrix-induced autologous chondrocyte implantation (MACI) in the knee
Authors:Davide?Enea  Stefano?Cecconi  Alberto?Busilacchi  Sandra?Manzotti  Rosaria?Gesuita  Email author" target="_blank">Antonio?GiganteEmail author
Institution:(1) Department of Orthopedics, Polytechnic University of Marche, Via Tronto 10/A, 60020 Ancona, Italy;(2) Centre of Epidemiology, Biostatistics and Medical Information Technology, Polytechnic University of Marche, Via Tronto 10/A, 60020 Ancona, Italy;
Abstract:

Purpose  

Matrix-induced autologous chondrocyte implantation (MACI) has been in use for chondral defect repair since 2000, but to date, only little is known about its histological outcomes in the repair of knee cartilage defects. This prospective multicentre study aims to evaluate (1) the quality of the repair tissue obtained from biopsies taken during second-look arthroscopy and (2) the relationship between the histological outcome, the macroscopic appearance of the repair and the patients’ functional status.
Keywords:
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