Malignant perivascular epithelioid cell tumor involving the prostate |
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Authors: | Pan Chin-Chen Yang An-Hang Chiang Hung |
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Institution: | Department of Pathology, National Yang-Ming University, and Veterans General Hospital-Taipei, Taipei, Taiwan. ccpan@vghtpe.gov.tw |
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Abstract: | Perivascular epithelioid cell tumor (PEComa) is a neoplasm chiefly composed of HMB-45-positive epithelioid cells with clear-to-granular cytoplasm and a perivascular distribution. We describe such a tumor involving the prostate and seminal vesicle in a 46-year-old man. The tumor had characteristic histologic features of PEComa. Immunohistochemically, the tumor cells were positive for HMB-45 but negative for epithelial markers, Melan-A, and S100 protein. The tumor behaved in a malignant fashion, and the patient died of the disease 4 years after diagnosis. |
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