| 胶质源性神经营养因子在正常和炎症牙髓组织中的变化 |
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| 引用本文： | 陆群,郭敬俊,吴补领,宋俊峰. 胶质源性神经营养因子在正常和炎症牙髓组织中的变化[J]. 牙体牙髓牙周病学杂志, 2000, 10(4): 201-203 |
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| 作者姓名： | 陆群 郭敬俊 吴补领 宋俊峰 |
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| 作者单位： | 1. 第四军医大学口腔医学院,陕西,西安,710032
2. 第四军医大学神经生物教研室,陕西,西安,710032 |
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| 摘 要： | 目的：探讨胶质原性神经营养在子（ＧＤＮＦ）在牙髓炎症中的表达变化及意义。方法：应用免疫组织化学方法比较正常和炎症状态下,ＧＤＮＦ在牙髓组织中的变化。结果：正常牙髓组织ＧＤＮＦ染色呈阴性,郯性牙髓组织染ＧＤＮＦ呈阳笥,其主要分布在牙髓成牙本质细胞和成牙本质反应,与炎性牙髓组织再发芽有关。
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| 关 键 词： | 胶质源性神经营养因子 免疫组化 牙髓炎 |
| 修稿时间： | 1998-12-31 |
Changes of glial cell line derived neurotrophic factor in normal and inflamed dental pulp |
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| LU Qun,GUO Jing-jun,WU Bu-ling,et al. Changes of glial cell line derived neurotrophic factor in normal and inflamed dental pulp[J]. Chinese Journal of Conservative Dentistry, 2000, 10(4): 201-203 |
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| Authors: | LU Qun GUO Jing-jun WU Bu-ling et al |
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| Abstract: | AIM: To investigate effects of glial cell line derived neurotrophic factor (GDNF) on dental nerve regression during inflamed restoration stages of dental pulp. METHODS: To observe changes of GDNF in inflamed dental pulp, compared with that in normal dental pulp by immunohistochemistry. RESULTS: Expression of GDNF was mainly found in odontoblast layer and subodontoblast zone of inflamed dental pulp, while was not observed at Schwann cell and normal dental pulp. CONCLUSION: These results indicate that GDNF may take part in inflamed response of dental pulp, and have an essential role in nerve sprouting reactions. [ |
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| Keywords: | GDNF nerve regression immunohistochemistry |
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