Clinical course of disease and prognosis in patients with ischemic heart disease with stable angina pectoris,caused by stenosing coronary atherosclerosis (data from a a 20-year study

AIM: To study a course and prognosis of ischemic heart disease (IHD) with stable angina pectoris (SAP) caused by stenotic coronary atherosclerosis (SCA) by 20-year follow-up data. MATERIAL AND DATA: Prognosis of survival was made in 318 patients with SAP due to SCA. RESULTS: The results of a 20-year study show that prognosis in IHD patients depends on SAP severity (by the functional class), exercise tolerance (by the exercise test), severity of coronary bed affection and of left ventricular contractility affection as assessed by coronary- and ventriculography. If lethality of the test subjects was not higher than in the population, the patient had good prognosis associated with one-vessel lesion, normal myocardial contractile function, high exercise tolerance, absence of the leading risk factors. CONCLUSION: The multivariance analysis with stepwise selection enabled the design of the model of the integral prognostic index (IPI) for the studied patients. The IPI index under 1.86 suggests a favourable prognosis, 1.87-2.33--an intermediate prognosis and in IPI higher than 2.34--unfavourable prognosis. Early surgery is recommended for patients with high IPI.