Web resources facilitate drug discovery in treatment of COVID-19 |
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| Institution: | 1. Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China;2. International Joint Research Center for Intelligent Biosensor Technology and Health, Central China Normal University, Wuhan 430079, China;3. State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang 550000, China;4. Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, China |
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| Abstract: | The infectious disease Coronavirus 2019 (COVID-19) continues to cause a global pandemic and, thus, the need for effective therapeutics remains urgent. Global research targeting COVID-19 treatments has produced numerous therapy-related data and established data repositories. However, these data are disseminated throughout the literature and web resources, which could lead to a reduction in the levels of their use. In this review, we introduce resource repositories for the development of COVID-19 therapeutics, from the genome and proteome to antiviral drugs, vaccines, and monoclonal antibodies. We briefly describe the data and usage, and how they advance research for therapies. Finally, we discuss the opportunities and challenges to preventing the pandemic from developing further. |
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| Keywords: | Bioinformatics SARS-CoV-2 Sequence and structure Drug design Vaccines Monoclonal antibodies |
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