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鼻咽癌患者外周血淋巴细胞对有丝分裂原的反应
引用本文:黄添友 赵明伦. 鼻咽癌患者外周血淋巴细胞对有丝分裂原的反应[J]. 中国病理生理杂志, 1992, 8(2): 132-135
作者姓名:黄添友 赵明伦
作者单位:第一军医大学中西医结合研究所(黄添友),湛江医学院病理教研室(赵明伦),湛江医学院病理教研室(黄培春)
基金项目:广东省高等学校自然科学重点科研资助
摘    要:本文探讨了PHA和Con A体外诱导NPC病人和VCA-IgA抗体阳性及阴性者外周血T_4、T_8细胞的变化。结果表明,NPC病人的PBMC对上述二种有丝分裂原诱导T_4和T_8细胞的能力最低,VCA-IgA抗体阳性组次之,VCA-IgA抗体阴性组最高。同时还证实了PHA主要是诱导T_4细胞,而Con A则主要是诱导T_8细胞。

关 键 词:有丝分裂原类 EB病毒 鼻咽肿瘤

Responseability of T lymphocytes in the peripheral blood of nasopharyngeal carcinoma patiens to mitogens
Huang Tian-You,Zhao Ming-Lun,et al Institute of the integrated traditional and western medicine,first military medical university,Guangzhou. Responseability of T lymphocytes in the peripheral blood of nasopharyngeal carcinoma patiens to mitogens[J]. Chinese Journal of Pathophysiology, 1992, 8(2): 132-135
Authors:Huang Tian-You  Zhao Ming-Lun  et al Institute of the integrated traditional  western medicine  first military medical university  Guangzhou
Abstract:PHA and Con A induced T_4 and T_8 cells of the peripheral blood of the nasopharyngeal carcinoma(NPC)patients and those of Epstein-Barr virus seropositive and seronegative individuals in vitro were investigated. The results showed that the res ponse ability of lymphocytes to the mitogens was the lowest in the NPC patients and the highest in the seronegative individuals. This findings indicated that the PHA and Con A could induce T_4 and T_8 cells respectively in vitro.
Keywords:Mitogens  T lymphocytes  Epstein-Barr virus  Nasopharyngeal neoplasms
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