| 玉屏风多糖对小鼠化学性肝损伤的影响 |
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| 引用本文： | 陈方军,李俊,王佳佳.玉屏风多糖对小鼠化学性肝损伤的影响[J].安徽医科大学学报,2011,46(1):49-52. |
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| 作者姓名： | 陈方军 李俊 王佳佳 |
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| 作者单位： | 安徽医科大学药学院,合肥,230032;安庆医药高等专科学校,安庆,246052;安徽医科大学药学院,合肥,230032 |
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| 摘 要： | 目的 观察玉屏风多糖(YPF-P)对D-氨基半乳糖(D-Gal)致化学性肝损伤小鼠血清、肝组织中丙氨酸氨基转移酶(ALT)、天门冬酸氨基转移酶(AST)、超氧化物歧化酶(SOD)、谷胱甘肽(GSH)、丙二醛(MDA)含量以及TNF-α表达水平的影响,探讨YPF-P对D-Gal致小鼠化学性肝损伤的作用机制.方法 经预防给...
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| 关 键 词： | 肝疾病/化学诱导 肿瘤坏死因子-α 脂质过氧化作用/药物作用 |
Effects of polysaccharides from Yu-Ping-Feng powder on chemical liver injury in mice |
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| Chen Fangjun,Li Jun,Wang Jiajia.Effects of polysaccharides from Yu-Ping-Feng powder on chemical liver injury in mice[J].Acta Universitis Medicinalis Anhui,2011,46(1):49-52. |
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| Authors: | Chen Fangjun Li Jun Wang Jiajia |
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| Institution: | Chen Fangjun1,2,Li Jun1,Wang Jiajia1(1Pharmacy School,Anhui Medical University,Hefei 230032,2Anqing Medical and Pharmaceutical College,Anqing 246052) |
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| Abstract: | Objective To investigate the effects of polysaccharides from Yu-Ping-Feng powder(YPF-P)on chemical liver injury induced by D-Gal in mice.Methods The model of mice chemical liver injury was induced by D-Gal on day 7 after treatment with YPF-P.The levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST)in serum and the contents of malondiadehyde(MDA),glutathione(GSH),superoxide dismutase(SOD)in liver homogenate were measured by using of spectrophotometers.Immunohistochemistry was used to detect... |
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| Keywords: | liver diseases/chemically induced tumor necrosis factor-alpha lipid peroxidation/drug effects |
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