| IL-17、hs-CRP联合检测在急性冠脉综合征中的意义 |
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| 引用本文： | 韦德宇,丁晓梅,苏浩,胡昊,陈东.IL-17、hs-CRP联合检测在急性冠脉综合征中的意义[J].安徽医药,2011,15(3):338-340. |
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| 作者姓名： | 韦德宇 丁晓梅 苏浩 胡昊 陈东 |
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| 作者单位： | 安徽医科大学附属省立医院心内科;安徽医科大学附属省立医院心内科;安徽省心血管病研究所,安徽,合肥,230001 |
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| 摘 要： | 目的观察IL-17、hs-CRP在急性冠脉综合征(ACS)患者血清中的水平变化,同时观察两者是否存在相关性,推测IL-17与斑块不稳定性的关系。方法选择113例患者分为四组:急性心肌梗死(AMI)40例,不稳定型心绞痛(UA)31例,稳定型心绞痛(SAP)18例,胸痛综合征(CPS)24例。患者入院后立即留取静脉血标本离心,存于-80℃的冰箱,采用ELISA法集中检测患者血清中的IL-17、hs-CRPc、TNI、CK-MB水平。结果 AMI组和UA组外周血清IL-17水平分别为(37.04±9.92)(、30.11±5.67)ng.L-1,明显高于SAP组的(20.95±5.08)ng.L-1和CPS组(15.81±7.65)ng.L-1(P<0.01)。AMI组和UA组患者hs-CRP水平分别为(39.21±14.42)(、11.57±3.71)mg.L-1,明显高于SAP组的(3.53±4.45)mg.L-1和CPS组(2.94±3.97)mg.L-1(P<0.05)。IL-17与hs-CRP Spearman相关系数r=0.364(P<0.001)。结论在ACS患者中血清中IL-17水平明显升高,与hs-CRP呈正相关,推测IL-17与动脉粥样硬化斑块不稳定性有关,参与了ACS的发病。
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| 关 键 词： | IL-17 hs-CRP 急性冠脉综合征 动脉粥样硬化 斑块 |
Significance of IL-17 and hs-CRP detected in patients with acute aoronary syndrome |
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| WEI De-yu,DING Xiao-mei,SU Hao,HU Hao,CHEN Dong.Significance of IL-17 and hs-CRP detected in patients with acute aoronary syndrome[J].Anhui Medical and Pharmaceutical Journal,2011,15(3):338-340. |
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| Authors: | WEI De-yu DING Xiao-mei SU Hao HU Hao CHEN Dong |
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| Institution: | WEI De-yu1,DING Xiao-mei1,2,SU Hao1,HU Hao1,CHEN Dong1(1.Department of Cardiology,Anhui Provincial Hospital Affiliated to Anhui Medical University,2.Institute of Cardiovascular Research,Hefei,Anhui 230001,China) |
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| Abstract: | Aim To observe the changes of IL-17 and hs-CRP in patients with acute coronary syndrome(ACS),and whether there was correlation between the two or not,and to investigate the relationship between IL-17 and the instability of plaque.Methods 113 patients were divided into 4 groups:40 cases with acute myocardial infarction(AMI),31 cases with unstable angina(UA),18 patients with stable angina pectoris(SAP),and 24 patients with chest pain syndrome(CPS).All were taken blood from immediately after admission in,and c... |
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| Keywords: | IL-17 hs-CRP |
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