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琥珀酸美托洛尔缓释片治疗原发性高血压60例分析
引用本文:张峰. 琥珀酸美托洛尔缓释片治疗原发性高血压60例分析[J]. 安徽医药, 2011, 15(3): 362-363
作者姓名:张峰
作者单位:安徽省宿州市立医院干部病房心内科,安徽,宿州,234000
摘    要:目的应用琥珀酸美托洛尔缓释片治疗轻、中度原发性高血压,观察其疗效。方法将60位轻、中度原发性高血压病人随机分为两组,每组30人。治疗组用琥珀酸美托洛尔缓释片47.5 mg,每日1次口服,每周随访1次,若2周无效者改用95 mg,每日1次口服4,周为1个疗程;对照组采用苯磺酸氨氯地平2.5~5 mg每日1次口服,每周随访1次4,周为1个疗程。结果治疗组患者,琥珀酸美托洛尔缓释片治疗4周末,治疗前、后血压值及心率比较,差异有统计学著意义(P<0.05);对照组患者治疗前、后血压值及心率比较,差异有统计学意义(P<0.05);将治疗组和对照组用药前、后的心率变化进行比较,前者优于后者,差异有统计学意义(P<0.05)。结论琥珀酸美托洛尔缓释片可持续平稳降压24 h以上,是治疗高血压的有效药物之一。

关 键 词:原发性高血压  美托洛尔  疗效比较

Essential hypertension treatment with metoprolol succinate sustained-release tablets: an analysis of 60 cases
ZHANG Feng. Essential hypertension treatment with metoprolol succinate sustained-release tablets: an analysis of 60 cases[J]. Anhui Medical and Pharmaceutical Journal, 2011, 15(3): 362-363
Authors:ZHANG Feng
Affiliation:ZHANG Feng (Department of Cardiology,Suzhou Municipal Hospital,Anhui 234000,China)
Abstract:Aim To observe the effects of metoprolol succinate sustained-release tablets in treating mild to moderate essential hypertension.Methods 60 adults with mild and moderate essential hypertension were randomly divided into two groups of 30 patients:the treatment group metoprolol succinate sustained-release tablets oral 47.5 mg once a day,one time follow-up a week.Two weeks if no change to ineffective use of metoprolol succinate sustained-release tablets,95 mg was given orally once a day,4 weeks a course of tre...
Keywords:essential hypertension  metoprolol  comparative effectiveness  
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