基于因子分析的女性肺一氧化碳弥散量与地理因素的关系

目的为制定成年女性肺一氧化碳弥散量参考值的统一标准提供科学依据。方法收集了中国用单次呼吸测量法测定68个单位的15549例健康成年女性肺一氧化碳弥散量参考值。运用相关分析的方法研究了其与海拔高度（X1）、年日照时数（X2）、年平均气温（X3）、气温年较差（X4）、年平均相对湿度（X5）、年降水量（X6）、年平均风速（X7）、年平均总云量（X8）的关系。结果发现海拔高度是影响成年女性肺弥散功能最主要的因素，随着海拔高度的增加而成年女性肺一氧化碳弥散量参考值也在增加。运用因子分析将8个地理因素综合为3个公共因子F1、F2、F3用其得分值代替推导出的回归模型为：Y-24．284＋0．004687F1-0．009473 F2—0．005065F3±5．86。结论如果知道了中国某地的地理指标，用此模型可以估算出这个地区的成年女性肺一氧化碳弥散量参考值，依据女性肺一氧化碳弥散量参考值与地理因素的依赖关系把中国分为青藏区，西南区，西北区，东南区，华北区，东北区等6个地区。

The geography distribution rule of Chinese adult women's pulmonary diffusion function based on factor analysis

Objective To supply a basis for uniting the reference value of Chinese adult women＇s pulmonary diffusion function. Methods A research is made about the relationship between the reference value of 15549 cases of Chinese adult women＇s Diffusion capacity for carbon monoxide of lung（DLCO） which are determined by single breath method, and eight geographical factors in Chinese areas , using the method of factor analysis. Results It is found that altitude is the main factor affecting the reference value of Chinese adult women＇s DLCO. As the altitude increases gradually, the reference value increases gradually（r1 = 0. 7814）. Eight geographical factors have been changed into three public factors-F1. F2, F3, by the Factor Analysis, a regression equation has been referred with ^ their value instead of the original data points： Y = 24. 284 ＋ 0. 004 687F1 -- 0. 009 473F2 -- 0. 005 065F3 ± 5. 86. Conclusion If geographical values are obtained in some areas, the reference value of Chinese adult women＇s DLCO in this area can be reckoned using the regression equation . Furthermore, similar to the reference value of Chinese presenile men＇s hematocrit, taking the altitude as the main dividing basis and considering effects of other geographical factors and population distribution, China can be divided into six regions： Qingzang, Southwest, Northwest, Southeast, North and Northeast region