| 从肺肠微生态变化研究肺与大肠的相关性 |
| |
| 引用本文： | 郑旭锐,杨宇,郑秀丽,周新颖,丁维俊,刘旺华. 从肺肠微生态变化研究肺与大肠的相关性[J]. 中医杂志, 2011, 52(10): 865-867 |
| |
| 作者姓名： | 郑旭锐 杨宇 郑秀丽 周新颖 丁维俊 刘旺华 |
| |
| 作者单位： | 成部中医药大学基础医学院,四川省成都市十二桥路37号,610075 |
| |
| 基金项目： | 国家重点基础研究发展计划("973"计划)资助项目 |
| |
| 摘 要： | 目的从微生态角度探索"肺与大肠相表里"的机制。方法将40只Wistar大鼠随机分为空白对照组、肺病组(过敏性哮喘)、肠病组(便秘)和肺肠同病组(过敏性哮喘合便秘),每组10只,收集各组大鼠的支气管肺泡灌洗液和粪便样本,进行肺部和肠道菌群主要微生物种类与含量检测。结果与空白对照组比较,肺病组、肺肠同病组大鼠的肺部菌群及3组大鼠的肠道菌群差异均有统计学意义(P<0.01);肠病组大鼠的肺部菌群与肺病组差异有统计学意义(P<0.05或P<0.01);肺肠同病组大鼠肺部菌群与肺病组比较差异有统计学意义(P<0.01),且肠道菌群与肠病组比较差异亦有统计学意义(P<0.05或P<0.01)。结论肺病状态下可导致肠道菌群变化,肠病也可影响肺部菌群的变化,为"肺与大肠相表里"提供部分微生态学实验依据。
|
| 关 键 词： | 肺与大肠相表里 菌群 微生态 哮喘 便秘 |
Correlation between the Lung and Large Intestine from the Micro-ecological Changes of Lung and Intestinal Flora |
| |
| ZHENG Xurui,YANG Yu,ZHENG Xiuli,ZHOU Xinying,DING Weijun,LIU Wanghua. Correlation between the Lung and Large Intestine from the Micro-ecological Changes of Lung and Intestinal Flora[J]. Journal of Traditional Chinese Medicine, 2011, 52(10): 865-867 |
| |
| Authors: | ZHENG Xurui YANG Yu ZHENG Xiuli ZHOU Xinying DING Weijun LIU Wanghua |
| |
| Affiliation: | ZHENG Xurui,YANG Yu,ZHENG Xiuli,ZHOU Xinying,DING Weijun,LIU Wanghua(College of Preclinical Medicine,Chengdu University of Chinese Medicine,Chengdu 610075) |
| |
| Abstract: | Objective To explore the mechanism of the exterior-interior relation between lung and large intestine from the micro-ecology. Methods Forty Wistar rats were randomized in blank control group,lung disease group (allergic asthma),bowel disease group (constipation),and lung-intestine disease group (allergic asthma and constipation),with 10 in each. The bronchoalveolar lavage fluid and fecal samples of all rats were collected for determining the main microbial types and contents of lung and intestinal flora and... |
| |
| Keywords: | exterior-interior relation between lung and large intestine flora micro-ecology asthma constipation |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
