三维适形放疗配合腔内后装治疗宫颈癌的 效果

 目的探讨三维适形放疗配合腔内后装治疗宫颈癌的临床疗效及放疗并发症。方法60例宫颈癌随机分 为两组。适形组30例采用6MVX线适形放疗,全盆腔DT40Gy后重新定位,重新作治疗计划继续照射至50Gy,有 局部宫旁残留者缩野推量到60Gy。腔内后装治疗A点总剂量30Gy/5次。常规组30例则采用全盆腔放疗40Gy 后改为盆腔四野照射10Gy，有局部宫旁残留者缩野推量到60Gy。腔内后装治疗A点总剂量（30～36）Gy/（ 5～6）次。两组均作同期化疗。 结果适形组和常规组1、2、3年生存率分别为96.7％、93.3％、90.0％和 86.6%、76.7％、70%(P=0.04、P=0.02和P=0.02), 差异有统计学意义。两组不良反应比较，适形组Ⅰ～Ⅱ 级放射性膀胱炎、直肠炎及盆腔纤维化发生率低于常规组(P=0.007、P=0.006和P=0.003)),其他不良反应 相似。 结论全程三维适形放疗配合腔内后装治疗加同期化疗是治疗宫颈癌的有效肯定的方法，能提高近 期生存率，晚期并发症较常规放疗低。

Effect of Three Dimensional Conformal Radiotherapy Combined with Intracavitary Brachtherapy in Treatment of Cervical Cancer

Objective To explore the effect and complications of all course three dimensional conformal radiotherapy(3DCRT) combined with intracavitary brachytherapy in the treatment of cervical cancer.Methods Sixty cervical cancer patients were randomly divided randomly into two groups.First,all patients accepted 3D conformal radiotherapy in the 3DCRT group,when whole pelvic received 40Gy,a planning CT scan of each patient was obtained.And second 3DCRT therapy plans were taken.Then continued to irradiate with 50Gy.Fin...