| 原发性硬化性胆管炎的研究 |
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| 引用本文： | 乔丽娟,周新民,韩英,樊代明. 原发性硬化性胆管炎的研究[J]. 胃肠病学和肝病学杂志, 2009, 18(7): 587-590 |
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| 作者姓名： | 乔丽娟 周新民 韩英 樊代明 |
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| 作者单位： | 第四军医大学西京消化病医院国家肿瘤重点实验室,陕西,西安,710032 |
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| 摘 要： | 原发性硬化性胆管炎（PSC）是一种自身免疫性疾病，其发病机制尚不明确。PSC诊断的金标准是内窥镜下逆行胆管造影技术（ERCP）及磁共振胰胆管造影术（MRCP）。PSC的治疗方法很多，包括药物治疗和肝移植。药物多推荐熊去氧胆酸，但效果欠佳。目前认为肝移植仍是治愈PSC的惟一选择。本文对PSC的研究及治疗进展作一概述。
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| 关 键 词： | 原发性硬化性胆管炎 UDCA 肝移植 |
The study of primary sclerosing cholangitis |
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| QIAO Lijuan,ZHOU Xinmin,HAN Ying,FAN Daiming. The study of primary sclerosing cholangitis[J]. Chinese Journal of Gastroenterology and Hepatology, 2009, 18(7): 587-590 |
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| Authors: | QIAO Lijuan ZHOU Xinmin HAN Ying FAN Daiming |
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| Affiliation: | (Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, Xi＇an 710032, China) |
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| Abstract: | Primary sclerosing cholangitis （PSC） is an autoimmune disease with unknown etiology. Its diagnosis primarily based on endoscopic retrograde cholangiography （ERCP） and magnetic resonance cholangiography （MRCP）. Current therapies include medical therapy and liver transplantation. Medical therapy has recommended ursodeoxycholic acid, however, the effect is not good enough. Liver transplantation is still the only choice to cure PSC so far. The present review stated the recent achievements on the research and management of PSC. |
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| Keywords: | UDCA |
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