Effects of curved-walking training on curved-walking performance and freezing of gait in individuals with Parkinson's disease: A randomized controlled trial |
| |
| Institution: | 1. Department of Physical Therapy and Assistive Technology, National Yang-Ming University, Taipei, Taiwan, ROC;2. Department of Rehabilitation, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, ROC;3. Department of Neurology, Chang Gung Memorial Hospital, Linkou, Taiwan, ROC;4. Department of Neurology, Mackay Memorial Hospital, Taipei, Taiwan, ROC;1. Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Bangalore, India;2. Department of Physical Therapy, College of Applied Health sciences, University of Illinois, Chicago, IL;3. Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, India;4. Department of Neurological Rehabilitation, National Institute of Mental Health and Neurosciences, Bangalore, India;1. KU Leuven, Department of Rehabiliation Sciences, Neuromotor Rehabilitation Research Group, Leuven, Belgium;2. Tel Aviv Sourasky Medical Center, Department of Neurology, Center for the Study of Movement, Cognition, and Mobility, Tel Aviv, Israel;3. University of Bologna, Department of Electrical, Electronic and Information Engineering – Guglielmo Marconi, Bologna, Italy;4. University of Sydney, Faculty of Health Sciences, Clinical and Rehabilitation Sciences Research Group, Sydney, Australia;5. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;6. Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel;1. IDC Hermitage-Capodimonte – Napoli, Italy;2. Department of Neurology, Institute of Research and Medical Care, IRCCS San Raffaele, Rome, Italy;3. Department of Neurosciences, University of Genoa, Genoa, Italy;4. Department of Neurosciences University of Messina, Messina, Italy;5. CeSI-Centro Studi Invecchiamento Fondazione Università Gabriele D''Annunzio, Chieti, Italy;6. Neurologia Istituto Mediterraneo Neuromed, Isernia, Italy;7. U.O. Neurologia Ospedale Civile Maggiore, Borgo Trento, Verona, Italy;8. Clinica Neurologica I Policlinico Universitario, Catania, Italy;9. Novartis Pharma Italia, Medical Department, Origgio, Italy;10. Medidata srl, Modena, Italy;11. Department of Medicine and Surgery, University of Salerno, Salerno, Italy;12. Department for Parkinson''s Disease, IRCCS San Camillo, Venice, Italy;1. Department of Physical Therapy, Federal University of Rio Grande do Norte, Natal, Brazil;2. Institute of Physical Activity and Sports Science, Cruzeiro do Sul University, São Paulo, Brazil;3. Department of Integrated Medicine, Federal University of Rio Grande do Norte, Natal, Brazil |
| |
| Abstract: | IntroductionThe purpose of this study was to investigate the effects of curved-walking training (CWT) on curved-walking performance and freezing of gait (FOG) in people with Parkinson's disease (PD).MethodsTwenty-four PD subjects were recruited and randomly assigned to the CWT group or control exercise (CE) group and received 12 sessions of either CWT with a turning-based treadmill or general exercise training for 30 min followed by 10 min of over-ground walking in each session for 4–6 weeks. The primary outcomes included curved-walking performance and FOG. All measurements were assessed at baseline, after training, and at 1-month follow-up.ResultsOur results showed significant improvements in curved-walking performance (speed, p = 0.007; cadence, p = 0.003; step length, p < 0.001) and FOG, measured by a FOG questionnaire (p = 0.004). The secondary outcomes including straight-walking performance (speed, cadence and step length, p < 0.001), timed up and go test (p = 0.014), functional gait assessment (p < 0.001), Unified Parkinson's disease Rating Scale III (p = 0.001), and quality of life (p < 0.001) were also improved in the experimental group. We further noted that the improvements were maintained for at least one month after training (p < 0.05).ConclusionA 12-session CWT program can improve curved-walking ability, FOG, and other measures of functional walking performance in individuals with PD. Most of the improvements were sustained for at least one month after training. |
| |
| Keywords: | Curved-walking Freezing of gait Turning-based treadmill training Parkinson's disease |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
