糖尿病患者血清甲状腺激素的变化及其意义

目的：探讨糖尿病患者血清甲状腺激素水平的变化及其临床意义。方法：用放射免疫法测定受试者血清T3，T4，FT3，FT4，TSH的水平，用己糖激酶法测定血糖。结果：糖尿病患者，尤其是有并发症者，血清T3，FT3水平明显降低（P＜0．01），T4，FT4，TSH变化不明显（P＞0．05），治疗后T3，FT3明显上升（P＜0．001），T3，FT3与FBG，PBG呈负相关（P＜0．001）,结论：对糖尿病患者测定血清T3，FT3，T4，FT4对糖尿病病情估计，判断预后及疗效有重要意义。

THE CHANGES AND SIGNIFICANCE OF THYROID HORMONE IN SERUM OF DIABETICS

Objective: To study the changes and clinical significance of thyroid hormone in serum of diabetics.Methods: The changes of surum-level T 3,T 4,FT 3,FT 4 and TSH in examinee by RIA were observed.The blood glucose were observed by methods of hexokinase.Rusultes: In diabetics, especially in complication cases, T 3 and FT-3 significantly decreased(P<0.01)T 4,FT 4,TSH remained intact(P>0.05).After treatment,T 3,FT 3 significantly increased(P<0.001). T 3,FT 3 were negative correlation with FBG,PBG(P<0.001). Conclusion: Serum-level T 3,FT 3,T 4 and FT 4 have important significance in estimation of the cases, prognosis and treatment in diabetic patients.