| 儿童炎症性肠病11例 |
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| 引用本文： | 丘小汕,余慕雪,莫清萍,陈志凤,卢亚亚,沈振宇. 儿童炎症性肠病11例[J]. 实用儿科临床杂志, 2010, 0(7) |
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| 作者姓名： | 丘小汕 余慕雪 莫清萍 陈志凤 卢亚亚 沈振宇 |
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| 作者单位： | 中山大学附属第一医院儿科; |
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| 摘 要： | 目的探讨儿童炎症性肠病(IBD)的临床特点,以提高对儿童IBD的认识。方法对1995年1月-2005年12月本院收治的11例IBD患儿的临床资料进行回顾性分析。结果11例IBD患儿中克罗恩病(CD)8例,溃疡性结肠炎(UC)3例;男9例,女2例;发病年龄1个月～12岁9个月(中位年龄6岁)。11例IBD患儿均无阳性家族史。临床表现为贫血9例(81.8%),消瘦、腹痛各8例(72.7%),发热7例(63.6%),腹泻6例(54.5%),便血5例(45.5%)。实验室检查11例(100%)患儿均有CRP增高,ESR升高10例(90.9%),白细胞升高8例(72.7%)。病理结果表现为浅表小溃疡7例(63.6%)、黏膜慢性炎症6例(54.5%),患儿均未见非干酪样肉芽。其中10例予5-氨基水杨酸或柳氮磺胺吡啶、糖皮质激素治疗后缓解。结论IBD可在婴幼儿期发病,其诊断应根据临床表现、血液学指标、消化内镜及组织病理学等资料进行综合评价。如临床高度怀疑IBD,实验室检查虽无典型病理改变,在除外感染性疾病和其他自身免疫性疾病的基础上,可行诊断性治疗。
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| 关 键 词： | 炎症性肠病 克罗恩病 溃疡性结肠炎 儿童 |
Inflammatory Bowel Disease in 11 Children |
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| QIU Xiao-shan,YU Mu-xue,MO Qing-ping,CHEN Zhi-feng,LU Ya-ya,SHEN Zhen-yu. Inflammatory Bowel Disease in 11 Children[J]. Journal of Applied Clinical Pediatrics, 2010, 0(7) |
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| Authors: | QIU Xiao-shan YU Mu-xue MO Qing-ping CHEN Zhi-feng LU Ya-ya SHEN Zhen-yu |
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| Affiliation: | QIU Xiao-shan,YU Mu-xue,MO Qing-ping,CHEN Zhi-feng,LU Ya-ya,SHEN Zhen-yu(Department of Pediatrics,the First Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510080,Guangdong Province,China) |
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| Abstract: | Objective To explore the clinical features of inflammatory bowel disease (IBD) in children and to improve the recognition of IBD in children.Method The clinical data of 11 pediatric inpatients with IBD,who were admitted to the First Affiliated Hospital of Sun Yat-Sen University from Jan.1995 to Dec.2005,were analyzed retrospectively.Results Among the 11 children with IBD,8 cases had Crohn's disease (CD) and 3 cases had ulcerative colitis (UC).There were 9 male and 2 female.The age of onset ranged from 1 mon... |
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| Keywords: | inflammatory bowel disease Crohn's disease ulcerative colitis child |
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