养精胶囊治疗弱精子症的临床观察

目的探讨养精胶囊治疗弱精子症的疗效与安全性。方法245例弱精子症患者随机分为治疗组195例与对照组50例,治疗组口服养精胶囊,对照组服用五子衍宗丸,治疗90天后评定疗效。结果治疗组总有效率为88.68%,对照组总有效率71.11%,2组总有效率有显著性差异(P<0.01)。治疗组治疗后前向运动精子的比例逐渐增加,与治疗前比较有显著性差异(P<0.01);对于合并少精子症,精子密度大于500万/mL,养精胶囊能增加精子密度,与治疗前比较有显著性差异(P<0.01);增加精浆果糖的含量,与治疗前比较有显著性差异(P<0.01)。2组治疗期间均无严重不良事件发生。结论养精胶囊治疗弱精子症疗效显著,对于精子密度大于500万/mL的少弱精子症,能显著增加精子密度,无严重不良反应。 

Clinical Observation on Treatment of Oligospernmtism with Yangjing Capsule

OBJECTIVE To investigate into the effect and safety of Yangjing Capsule in the treatment of oligospermatism.METHOD 245 patients with oligospermatism were randomly divided into a treatment group of 195 patients and a control group of 50 patients,who took Yangjing Capsule and Wuzi Yanzong Pill respectively for 90 days.RESULT The effective rates of the treatment group and control group were 88.68% and 71.11% respectively,with marked difference(P<0.01).The forward motility sperm increased gradually in the treatment group after the treatment,with marked difference as compared with the sperm count before the treatment(P<0.01).For patients with oligospermatism as a complication with a sperm density of over 5,000,000/mL,Yangjing Capsule could increase the sperm density,with marked difference as compared with the sperm count before the treatment(P<0.01).Seminal plasma fructose level was also increased,with marked difference as compared with the level before the treatment.No serious undesirable accident occurred in both group.CONCLUSION Yangjing Capsule is very effective for oligospermatism and can markedly increase sperm density for patients with a sperm density of over 5,000,000/mL,with no serious side effect.